Significant Scientific Publications

  • Chavin W, Schlesinger W. Some potent melanin depigmentary agents in the black goldfish. Naturwissenschaften 1966; 53:413–14
  • Frenk E, Pathak MA, Szabo G, Fitzpatrick TB. Selective action of mercaptoethylamines on melanocytes in mammalian skin: experimental depigmentation. Arch Dermatol 1968; 97:465–77

  • Bleehen S, Pathak MA, Hori Y, Fitzpatrick TB. "Depigmentation of skin with 4-isopropylcatechol, mercaptoamines, and other compounds". J Invest Dermatol. 1968; 50: 103–17

  • Tatsuta M. et al. Inhibition by cysteamine of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.  Int J Cancer. 1989; 44:529–533 

  • Tatsuta M, Iishi H, Baba M, Taniguchi H. Tissue norepinephrine depletion as a mechanism for cysteamine inhibition of colon carcinogenesis induced by azoxymethane in Wistar rats. Int J Cancer 1989; 44:1008–11

  • Ip C et al. Comparison of selenium and sulfur analogs in cancer prevention. Carcinogenesis. 1992; 13 (7) 1167-1170

  • Watanabe M. et al. Rapid inactivation of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a potent mutagen in chlorinated drinking water, by sulfhydryl compounds. Mutat Res. 1994 ; 312 (2): 131-138

  • Qiu L, Zhang M, Sturm RA et al. Inhibition of melanin synthesis by cysteamine in human melanoma cells. J Invest Dermatol 2000; 114:21–7

  • Hoffmann GR, Shorter RA, Quaranta JL, McMaster PD. Two mechanisms of antimutagenicity of the aminothiols cysteamine and WR-1065 in Saccharomyces cerevisiae. Toxicol In Vitro 1999; 13:1–9

  • Inano H et al., Inhibitory effects of WR-2721 and cysteamine on tumor initiation in mammary glans of pregnant rats by radiation. Radiat.Res. 2000; 153(1):68-74

  • Gupta AK, Gover MD, Nouri K, Taylor S. The treatment of melasma: a review of clinical trials. J Am Acad Dermatol 2006; 55:1048– 65

  • Fujisawa T et al.  Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatin cancer. PLoS One. 2012; 7(4):e34437

  • Rajaratnam R, Halpern J, Salim A, Emmett C. Interventions for melasma. Cochrane Database Sys Rev 2010; 7: CD003583

  • Hsu C, Ahmadi S, Pouramadi M, Ali Mahdi H. Cysteamine cream as a new skin depigmenting product. Presented at the 17th Meeting of the European Society for Pigment Cell Research, Geneva, Switzerland, 11–13 September 2012

  • Hsu C, Pouramadi M, Ahmadi S, Ali Mahdi H. Cysteamine cream as a new skin depigmenting agent. Presented at the European Academy of Dermatology Annual Meeting, Prague, Czech Republic, 27–30 September 2012

  • Hsu C, Ali Mahdi H, Pourahmadi M, Ahmadi S. Cysteamine cream as a new skin depigmenting product. Journal of the American Academy of Dermatology, 2013, 68:4-1 AB189

  • Jutley GS, Rajaratnam R, Halpern J et al. Systematic review of randomized controlled trials on interventions for melasma: an abridged Cochrane review. J Am Acad Dermatol 2014; 70: 369–73
  • Mansouri P, Farshi S, Hashemi Z, Kasraee B. Evaluation of the efficacy of cysteamine 5% cream in the treatment of epidermal melasma: a randomized double-blind placebo-controlled trial. British Journal of Dermatology. 2015; 173, pp209–217
  • Farshi S., Mansouri P, Kasraee B. Efficacy of Cysteamine Cream in the treatment of melasma. Journal of Dermatological Treatment, July 2017

  •  

orders Scientispharma.com